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Updated: Feb 22, 2026

Defining Substrate Specificities for Lipase and Phospholipase Candidates
Published on: November 23, 2016
Burkholderia cepacia lipase: A versatile catalyst in synthesis reactions
Daniel A Sánchez1, Gabriela M Tonetto1, María L Ferreira1
1Planta Piloto de Ingeniería Química (PLAPIQUI), Universidad Nacional del Sur, CONICET, Bahía Blanca, Argentina.
Abstract:
The lipase from Burkholderia cepacia, formerly known as Pseudomonas cepacia lipase, is a commercial enzyme in both soluble and immobilized forms widely recognized for its thermal resistance and tolerance to a large number of solvents and short-chain alcohols. The main applications of this lipase are in transesterification reactions and in the synthesis of drugs (because of the properties mentioned above). This review intends to show the features of this enzyme and some of the most relevant aspects of its use in different synthesis reactions. Also, different immobilization techniques together with the effect of various compounds on lipase activity are presented. This lipase shows important advantages over other lipases, especially in reaction media including solvents or reactions involving short-chain alcohols.
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