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Related Experiment Videos

The Beta Blocker Heart Attack Trial: recruitment experience.

S Goldstein, R Byington

    Controlled Clinical Trials
    |December 1, 1987
    PubMed
    Summary

    The Beta Blocker Heart Attack Trial found that propranolol significantly reduced mortality in patients following a myocardial infarction. This beta blocker therapy proved effective in improving survival rates after a heart attack.

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    Area of Science:

    • Cardiology
    • Clinical Trials
    • Pharmacology

    Background:

    • Myocardial infarction (MI) poses a significant risk of mortality.
    • Beta blockers are a class of drugs used to manage cardiovascular conditions.
    • The need for effective post-MI treatments to reduce mortality is critical.

    Purpose of the Study:

    • To evaluate the efficacy of propranolol in reducing total mortality after myocardial infarction.
    • To determine the impact of beta blocker therapy on long-term survival in post-MI patients.

    Main Methods:

    • The Beta Blocker Heart Attack Trial (BHAT) enrolled 3837 patients within 5-21 days of experiencing a myocardial infarction.
    • Patients were recruited across 31 clinics, 134 hospitals, and 136 acute coronary care units.
    • A coronary care unit log was utilized to track patients for recruitment maximization and define the patient population.

    Main Results:

    • Propranolol was tested for its effectiveness in decreasing total mortality.
    • The trial aimed to establish the benefit of beta blocker treatment in a specific patient cohort.

    Conclusions:

    • The Beta Blocker Heart Attack Trial demonstrated the life-saving potential of propranolol post-myocardial infarction.
    • Beta blocker therapy, specifically with propranolol, is a valuable intervention for improving outcomes after a heart attack.

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