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Brucellosis: A lymphoma-like presentation.

Marcel Massoud1, Fouad Kerbage1, Leony Antoun1

  • 1Holy Spirit University of Kaslik, Medical School, Lebanon; CHU-Notre Dame Des Secours, Jbeil, Lebanon.

Asian Pacific Journal of Tropical Medicine
|September 26, 2017
PubMed
Summary

Brucellosis, a zoonotic infection, can present with unusual mesenteric and retroperitoneal lymphadenopathy. This case highlights the importance of considering brucellosis in patients with prolonged fever, even without typical symptoms.

Keywords:
BrucellosisMesenteric lymphadenopathiesRetroperitoneal lymphadenopathies

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Brucellosis is a prevalent global zoonotic infection caused by Brucella bacteria.
  • Transmission occurs through infected animals or contaminated food products like unpasteurized milk.
  • Clinical manifestations of brucellosis are diverse, ranging from systemic illness to asymptomatic cases.

Purpose of the Study:

  • To report a unique case of brucellosis presenting as mesenteric and retroperitoneal lymphadenopathy.
  • To emphasize the diagnostic considerations for brucellosis in endemic regions.

Main Methods:

  • Case presentation of a 52-year-old male with prolonged fever and abdominal pain.
  • Diagnostic workup included abdominal CT scans and blood cultures.
  • Treatment and follow-up imaging were performed.

Main Results:

  • Abdominal CT revealed mesenteric and retroperitoneal lymphadenopathies.
  • Blood cultures confirmed Brucella melitensis infection.
  • Follow-up CT showed complete resolution of lymphadenopathies after treatment.

Conclusions:

  • This is the first reported case of brucellosis presenting with both retroperitoneal and mesenteric lymphadenopathy.
  • Brucellosis should be suspected in endemic areas for prolonged fever, irrespective of typical clinical signs.
  • Prompt diagnosis and treatment led to complete resolution of lymphadenopathy.