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Bordetella bronchiseptica infection
M Ducours1, P Rispal1, M P Danjean2
1Service de médecine interne 2, centre hospitalier d'Agen, route de Villeneuve-sur-Lot, 47000 Agen, France.
Medecine Et Maladies Infectieuses
|September 26, 2017
Summary
Bordetella bronchiseptica infections primarily affect the elderly and present as respiratory illness. Early treatment is crucial, as antibiotic resistance is common, and mortality rates are significant.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Respiratory Medicine
Background:
- Bordetella bronchiseptica is an opportunistic pathogen.
- Hospitalized patients are susceptible to B. bronchiseptica infections.
- Limited data exists on clinical outcomes and treatment of B. bronchiseptica in humans.
Purpose of the Study:
- To describe the characteristics of patients hospitalized with B. bronchiseptica.
- To identify risk factors and clinical presentation of B. bronchiseptica infections.
- To evaluate antibiotic resistance patterns and treatment outcomes.
Main Methods:
- Retrospective monocentric study.
- Inclusion of all hospitalized patients with positive B. bronchiseptica tests from 2001-2015.
- Data collection on patient demographics, clinical symptoms, diagnostic methods, and antibiotic susceptibility.
Main Results:
- Nine patients were identified between 2001 and 2015.
- Risk factors included advanced age, immunodeficiency, and pre-existing respiratory conditions.
- Respiratory symptoms were universal, with significant antibiotic resistance observed (cephalosporins, monobactam, fosfomycin, penicillin A, trimethoprim/sulfamethoxazole).
- Four patients died, highlighting the severity of these infections.
- Treatment protocols remain undefined.
Conclusions:
- B. bronchiseptica infections predominantly impact the elderly population.
- Prompt and comprehensive treatment is recommended for all infected individuals.
- Addressing animal reservoirs is essential for public health.
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