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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
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Coronary artery calcium quantification on first, second and third generation dual source CT: A comparison study.

Marleen Vonder1, Gert Jan Pelgrim1, Sèvrin E M Huijsse2

  • 1University of Groningen, University Medical Center Groningen, Center for Medical Imaging North-East Netherlands (CMI-NEN), Groningen, The Netherlands.

Journal of Cardiovascular Computed Tomography
|September 26, 2017
PubMed
Summary

Coronary artery calcium (CAC) quantification is consistent across three dual-source computed tomography (DSCT) generations, ensuring reliable screening and progression studies. Detectability and scoring show minimal differences, with the latest generation offering the lowest variability.

Keywords:
Cardiovascular diseaseComputed tomographyCoronary atherosclerosisImage reconstructionImagingPhantom

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Area of Science:

  • Medical Imaging
  • Cardiovascular CT Technology
  • Radiology

Background:

  • Coronary artery calcium (CAC) quantification accuracy is crucial for screening and progression studies.
  • Potential differences in CAC quantification between successive CT scanner generations may affect study outcomes.
  • Vendor-specific CT system advancements necessitate comparative analysis.

Purpose of the Study:

  • To compare coronary artery calcium (CAC) quantification across three generations of dual-source computed tomography (DSCT) systems.
  • To evaluate the impact of technological evolution on CAC measurement consistency.
  • To ensure the reliability of CAC screening and progression studies utilizing different DSCT generations.

Main Methods:

  • Utilized three DSCT generations with anthropomorphic chest phantoms and specialized inserts.
  • Assessed detectability, Agatston score, and mass score using calcifications of varying sizes.
  • Investigated the effect of simulated coronary artery movement on calcium scoring.
  • Acquired data using prospective ECG-gating at 120 kVp, 90 reference mAs in sequential and high-pitch spiral modes.

Main Results:

  • No significant differences in calcification detectability were observed across the three DSCT generations.
  • Agatston scores for large calcifications showed no significant difference between the second and third DSCT generations.
  • Intra-scanner variability for Agatston and mass scores ranged from 1.4% to 8.3%, with the third generation exhibiting the lowest variability.

Conclusions:

  • All three DSCT generations demonstrate comparable detectability of coronary artery calcifications.
  • Median Agatston and mass scores varied by a maximum of 12.7% and 5.6%, respectively.
  • Advancements in DSCT technology maintain consistent CAC quantification across generations.