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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Desmosomes01:05

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The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein...
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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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A 3D Organotypic Melanoma Spheroid Skin Model
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Desmoplastic Melanoma

Anthony Maurice Kordahi1, Joshua B Elston1, Ellen M Robertson1

  • 1Division of Plastic Surgery, Department of Surgery, University of California San Diego; and University of South Florida Morsani College of Medicine, Tampa.

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|September 26, 2017
PubMed
Summary

No abstract available in PubMed .

Keywords:
desmoplasiadesmoplastic melanomaneurotropismskin cancerspindle cell

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