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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

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Hypertrophic obstructive cardiomyopathy-the Leipzig experience.

Jawad Khalil¹, Michael Kuehl², Pirose Davierwala¹

¹Department of Cardiac Surgery, Heart Centre, University of Leipzig, Leipzig, Germany.

Annals of Cardiothoracic Surgery

|September 26, 2017

Summary

This summary is machine-generated.

Surgical septal myectomy effectively reduces left ventricular outflow tract obstruction in hypertrophic obstructive cardiomyopathy (HOCM) patients, improving cardiac function and quality of life with low operative risk.

Keywords:

Hypertrophic obstructive cardiomyopathy (HOCM)concomitant procedures left ventricular outflow tract

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Area of Science:

Cardiology
Cardiac Surgery
Hypertrophic Cardiomyopathy Research

Background:

Management of hypertrophic obstructive cardiomyopathy (HOCM) involves medical therapy and surgical septal myectomy (SM) for left ventricular outflow tract obstruction (LVOTO).
The Leipzig Heart Center reports its experience in surgical HOCM management.

Purpose of the Study:

To evaluate the effectiveness and outcomes of surgical management for LVOTO in HOCM patients.
To analyze patient characteristics, surgical results, and long-term follow-up data.

Main Methods:

Retrospective analysis of 115 HOCM patients undergoing surgical treatment for LVOTO between 1997 and 2016.
Data collected from a surgical database, excluding patients with incomplete information.

Main Results:

The study included 115 patients (1.1:1 male:female ratio, mean age 60.8 years).
Dyspnea was the most common symptom (n=102), with 50% in NYHA class III.
Surgery reduced mean septal thickness by 15 mm and LVOT gradient by 9.7 mmHg, significantly improving NYHA classification, especially in class III patients.

Conclusions:

Surgical treatment for LVOTO in HOCM is effective in improving cardiac function and quality of life.
The procedure is associated with a low operative risk and favorable long-term outcomes.