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Egg-derived bioactive peptides with ACE-inhibitory properties: a literature update
Charlotte Grootaert1, Bea Matthijs, Stefan Voorspoels
1Department of Food Safety and Food Quality, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium. charlotte.grootaert@ugent.be john.vancamp@ugent.be.
Abstract:
Egg proteins contain a wide set of peptide sequences which have an impact on cardiovascular health. Their modes-of-action involve, among others, the inhibition of angiotensin-converting enzyme (ACE) and antioxidant and anti-inflammatory properties. In this review, we focus particularly on ACE-inhibition and discuss recent findings in: (i) production methods for egg protein-derived ACE-inhibitory peptides, (ii) in vitro functionality of these peptides, (iii) their intestinal digestion and absorption in order to reach the target tissue, (iv) the impact of ACE-inhibitory egg-derived peptides in vivo and (v) future perspectives for the implementation of egg-derived ACE-inhibitory peptides as functional foods.
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