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Fluorescent Sensors Based on Aggregation-Induced Emission: Recent Advances and Perspectives
Meng Gao1, Ben Zhong Tang1,2
1Guangdong Innovative Research Team, State Key Laboratory of Luminescent Materials & Devices, South China University of Technology , Guangzhou 510640, China.
ACS Sensors
|September 26, 2017
Summary
Aggregation-induced emission fluorogens (AIEgens) offer superior performance over traditional fluorescent sensors. These AIEgens provide enhanced sensitivity and photostability for advanced environmental and biomedical applications.
Area of Science:
- Materials Science
- Analytical Chemistry
- Biotechnology
Background:
- Conventional fluorescent sensors face limitations like self-quenching and poor photostability due to planar structures.
- Aggregation-caused quenching (ACQ) is a common issue in traditional fluorophores.
- Aggregation-induced emission fluorogens (AIEgens) overcome these limitations with high emission efficiency in aggregated states.
Purpose of the Study:
- To review the concept of AIE and turn-on sensing principles.
- To discuss recent examples of AIE sensors categorized by analyte types.
- To provide a future outlook on AIE sensor development.
Main Methods:
- Literature review of aggregation-induced emission (AIE) phenomena.
- Analysis of AIEgens' unique properties (high signal-to-noise ratio, photostability, large Stokes' shift).
- Categorization and discussion of AIE sensors based on target analytes.
Main Results:
- AIEgens exhibit high emission efficiency in the aggregated state, unlike ACQ fluorophores.
- AIE sensors offer advantages such as high signal-to-noise ratio, strong photostability, and large Stokes' shift.
- AIEgens provide unique opportunities for sensitive and reliable sensing applications.
Conclusions:
- AIEgens represent a significant advancement in fluorescent sensor technology.
- The unique properties of AIEgens enable improved performance in environmental monitoring, biological research, and disease diagnosis.
- Further research into AIE sensors promises exciting future developments in the field.
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