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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

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Published on: December 11, 2016

De-prescription.

Diane Portman¹

¹Moffitt Cancer Center.

Families, Systems & Health : the Journal of Collaborative Family Healthcare

|September 26, 2017

Summary

This summary is machine-generated.

Deprescribing aims to reduce medications for better patient outcomes. However, patients may resist this process due to fears of symptom return or reliance on medication for coping, causing challenges for clinicians.

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Area of Science:

Gerontology
Clinical Pharmacy
Patient Psychology

Background:

Deprescribing involves reducing or stopping medications to enhance patient function and quality of life.
Patients often exhibit resistance to deprescribing due to trust in clinicians and fear of symptom recurrence.
Medication use can be a coping mechanism or perceived as essential for health maintenance.

Purpose of the Study:

To explore patient resistance to deprescribing.
To understand the challenges faced by clinicians during deprescribing.
To identify strategies for improving patient-centered deprescribing.

Main Methods:

Qualitative analysis of patient-clinician interactions.
Surveys assessing patient attitudes towards deprescribing.
Literature review on barriers to medication discontinuation.

Main Results:

Patient resistance stems from fear of medical problems, medication reliance for coping, and beliefs about health benefits.
Clinicians experience patient distress and opposition during deprescribing attempts.
Successful deprescribing requires addressing patient concerns and building trust.

Conclusions:

Patient resistance is a significant barrier to effective deprescribing.
Addressing patient fears and expectations is crucial for successful medication reduction.
Further research is needed on communication strategies to facilitate deprescribing.