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Retention Improvement in Fluoride Application with Cold Atmospheric Plasma.

Y M Kim¹, H Y Lee², H J Lee²

¹1 Department of Oral Anatomy, School of Dentistry, Pusan National University, Yangsan, South Korea.

Journal of Dental Research

|September 26, 2017

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Cold atmospheric plasma (CAP) combined with acidulated phosphate fluoride (APF) gel significantly enhances fluoride uptake and retention on enamel. This combination treatment improves enamel

Area of Science:

Dental Materials Science
Biomaterials Engineering
Plasma Science

Background:

Fluoride application is a cornerstone of dental caries prevention.
Improving fluoride retention and efficacy remains a key objective in restorative dentistry.
Cold atmospheric plasma (CAP) is an emerging technology with potential biomodification applications.

Purpose of the Study:

To quantitatively assess fluoride uptake, retention, and acid resistance on human enamel treated with acidulated phosphate fluoride (APF) gel alone versus APF gel combined with CAP.
To investigate the effect of repeated CAP and APF treatments on enamel properties.

Main Methods:

Human enamel specimens were treated with 1.23% APF gel, with or without CAP, applied 4 times weekly.
Fluoride content was measured using an electron probe microanalyzer.

Keywords:

dental care dental caries fluoridation plasma gases preventive dentistry tooth demineralization

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Enamel demineralization resistance was assessed by measuring the calcium-to-phosphate ratio after acid challenge and storage in artificial saliva.

Main Results:

Fluoride uptake and retention were significantly higher in the APF + CAP group compared to the APF-only group.
Fluoride was detectable up to 4 weeks in the APF + CAP group, but not in the APF-only group.
Enamel treated with APF + CAP demonstrated superior resistance to demineralization, indicated by a higher calcium-to-phosphate ratio.

Conclusions:

Combining CAP with APF gel treatment enhances fluoride retention on enamel.
CAP-assisted fluoride application improves enamel's resistance to demineralization compared to APF gel alone.
This synergistic approach holds promise for advanced dental caries prevention strategies.