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Updated: Feb 22, 2026

Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue
Published on: May 17, 2018
Energy Through Motion: An Activity Intervention for Cancer-Related Fatigue in an Ambulatory Infusion Center
Linda Abbott1, Mary Catherine Hooke2
1University of Iowa Hospitals and Clinics.
Background:
Cancer-related fatigue (CRF) occurs in most people with cancer undergoing chemotherapy. Physical activity (PA) is safe and effective in reducing CRF in people with cancer. .
Objectives:
This project involved the implementation and evaluation of a three-month PA program to maintain or improve CRF and quality of life. .
Methods:
Activity trackers and resistance bands were provided to participants. Verbal instruction, printed material, activity videos, and text messages were used in this program. Participants completed a fatigue assessment; self-reported PA measure; and measure of attitudes, beliefs, and knowledge about sustaining regular PA pre- and postimplementation. .
Findings:
51 patients enrolled in the study, and 39 completed the program. Participants' fatigue did not worsen significantly during the three months, and self-reported activity levels increased, but not significantly. The activity tracker, text messages, and personal connection with nursing staff were reported to be helpful.
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