Related Experiment Video

Updated: Feb 22, 2026

MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method
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MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method

Published on: October 7, 2025

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MicroRNAs: Clinical Trials and Potential Applications


Nilesh Kalariya1, Kelly Brassil1, George Calin1

  • 1University of Texas MD Anderson Cancer Center.

Clinical Journal of Oncology Nursing
|September 26, 2017
PubMed

Insights

MicroRNAs are key molecules in cell health and cancer. Oncology nurses can educate patients on microRNA applications in cancer care.

Area of Science:

  • Biochemistry and Molecular Biology
  • Oncology

Background:

  • MicroRNAs (miRNAs) are small non-coding RNAs regulating gene expression.
  • Dysregulation of miRNAs is implicated in various pathophysiologic conditions, notably cancer.
  • The link between miRNAs and cancer has been a significant research focus since 2002.

Purpose of the Study:

  • To highlight the critical role of microRNAs in both normal cellular functions and cancer development.
  • To underscore the emerging clinical relevance of microRNAs in oncology.
  • To emphasize the educational role of oncology nurses regarding miRNA applications in cancer care.

Main Methods:

  • Literature review and synthesis of current research on microRNAs in oncology.
  • Analysis of the functional roles of microRNAs in carcinogenesis.
  • Exploration of the potential diagnostic and therapeutic applications of microRNAs.

Main Results:

  • MicroRNAs are fundamental regulators of cellular processes.
  • Aberrant miRNA expression patterns are hallmarks of many cancers.
  • MicroRNAs show promise as biomarkers and therapeutic targets in oncology.

Conclusions:

  • MicroRNAs are integral to understanding cancer biology.
  • Further research into microRNA functions may yield novel cancer treatments.
  • Oncology nurses are vital in communicating the potential of microRNAs to patients and families.
Keywords:
biomarkersmicroRNA-based clinical trialsmicroRNA-based therapeuticsmicroRNAs

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