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Outcomes of Esophageal Replacement: Gastric Pull-Up and Colonic Interposition Procedures
Catherine Jane Bradshaw1,2, Keren Sloan1, Anna Morandi2
1Department of Paediatric Surgery, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Insights
Gastric pull-up and colonic interposition for esophageal replacement show similar mortality. Colonic interposition had more septic complications and strictures, requiring more surgeries.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Surgical Outcomes
Background:
- Optimal surgical technique for esophageal replacement remains debated.
- Gastric pull-up and colonic interposition are common reconstructive methods.
Purpose of the Study:
- To compare surgical outcomes of gastric pull-up versus colonic interposition in pediatric esophageal replacement.
- To identify complications and long-term results associated with each technique.
Main Methods:
- Retrospective review of 50 children undergoing esophageal replacement surgery (2001-2015).
- Patients categorized into gastric pull-up (Group A) and colonic interposition (Group B).
- Data analyzed for indications, complications, and outcomes.
Main Results:
- Mortality rates were comparable (6%) between groups.
- Colonic interposition (Group B) showed higher rates of septic complications and anastomotic strictures.
- More patients in Group B required further surgery; 91.5% achieved full oral feeding within 6 months.
Conclusions:
- Gastric pull-up and colonic interposition demonstrate similar mortality and overall outcomes.
- Colonic interposition is linked to increased early septic complications, anastomotic strictures, and reoperation rates.
- Choice of technique may influence complication profile in pediatric esophageal replacement.
Aim:
No consensus exists about the optimal surgical technique for esophageal replacement. This study reports the surgical outcomes for the gastric pull-up and the colonic interposition procedures.
Materials And Methods:
A retrospective review of children undergoing esophageal replacement surgery between January 2001 and June 2015 across four different pediatric surgery centers was conducted. Data collected included indications, epidemiology, surgical technique, complications, and outcomes. Patients were divided into group A, those that had a gastric pull-up procedure and group B, those that had a colonic interposition procedure.
Results:
In total, 50 patients were included; 29 in group A and 21 in group B. Indications included esophageal atresia, caustic ingestion, and infective esophageal stricture. The median age at the time of surgery was 13 months. The mean length of follow-up was 5.2 years. Three patients died giving a mortality rate of 6%; 2 in group A and 1 in group B.In both groups, early postoperative complications included infective complications, such as wound infections, sepsis, and pneumonia (11), anastomotic leak (7), and respiratory complications (7). Late complications included adhesive bowel obstruction (2), anastomotic strictures (4), redundancy (1), and jejunostomy problems (1). Septic complications and anastomotic strictures occurred more frequently in group B. Further surgery was needed in eight patients; this was significantly higher in group B. Full oral feeding was achieved within 6 months in 91.5%.
Conclusion:
The gastric pull-up and colonic interposition have comparable mortality and outcomes. The colonic interposition was associated with a higher rate of early septic complications, anastomotic strictures, and need for further surgery.
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