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Updated: Feb 22, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Oral Appliance Therapy for Sleep Apnea.]
1Dental Clinic for Sleep Disorders(Apnea and Snoring), University Hospital of Dentistry, Tokyo Medical and Dental University, Japan.
Abstract:
Sleep apnea syndrome(SAS)was revealed to be a modern disease because of the skeletal morphology, lifestyle habit and mental stress of modern humans. Approximately 400 thousand SAS patients have been diagnosed and treated in Japan and numbers of potential SAS patients were estimated at more than 5 millions. Contemporary therapy for SAS is continuous positive airway pressure(CPAP)therapy in medical for moderate or severe SAS and oral appliance(OA)therapy in dental for mild SAS patients. However recent study shows OA therapy is effective even for moderate or severe SAS. In this review, outlines and current status of OA therapy will be discussed.
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