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Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica
P Piccardo1, M Ceroni, P Rodgers-Johnson
1Laboratory of Central Nervous System Studies, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD 20892.
Annals of Neurology
|January 1, 1988
Abstract:
The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T-lymphotropic virus type 1 were found.