Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Pressure Imbalances and Circulatory Shock01:24

Blood Pressure Imbalances and Circulatory Shock

1.7K
Disorders affecting blood volume, vascular tone, or vascular function can disrupt vascular homeostasis, including conditions like hypertension, hemorrhage, and shock.
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
1.7K
Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

Cardiopulmonary Resuscitation IV: Pharmacological Management

970
Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
970
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

634
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
634
Introduction Cardiac Emergencies01:30

Introduction Cardiac Emergencies

421
Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
421
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.1K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.1K
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

506
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
506

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond the protocol: adherence to ECPR selection criteria and outcomes after Out-of-Hospital Cardiac Arrest (OHCA)-insights from the German Cardiac Arrest Registry (G-CAR).

Clinical research in cardiology : official journal of the German Cardiac Society·2026
Same author

Letter to the Editor: 250th cardiac arrest center certification in Germany.

Clinical research in cardiology : official journal of the German Cardiac Society·2025
Same author

Criteria for the certification of Cardiac Arrest Centers in Germany.

Resuscitation·2021
Same author

[Quality indicators and structural requirements for Cardiac Arrest Centers-Update 2021].

Notfall & rettungsmedizin·2021
Same author

[Short version of the 2nd edition of the German-Austrian S3 guidelines "Cardiogenic shock complicating myocardial infarction-Diagnosis, monitoring and treatment"].

Der Anaesthesist·2020
Same author

[Acute myocardial infarction-actual issues].

Herz·2020
Same journal

[Heart and climate].

Herz·2026
Same journal

Multidimensional psychosocial screening in routine cardiac care: preliminary findings from a cross-sectional survey.

Herz·2026
Same journal

[Noise and the heart].

Herz·2026
Same journal

[The cardiovascular exposome: areas of action for prevention and practical cardiology].

Herz·2026
Same journal

Relationship between HAVOC score and new-onset atrial fibrillation in patients with ST elevation myocardial infarction.

Herz·2026
Same journal

Interventional treatment of atrioventricular valves.

Herz·2026
See all related articles

Related Experiment Video

Updated: Feb 22, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.7K

[Cardiogenic shock : Current evidence].

H Thiele1

  • 1Herzzentrum, Klinik für Innere Medizin/Kardiologie, Universität Leipzig, Strümpellstr. 39, 04289, Leipzig, Deutschland. holger.thiele@medizin.uni-leipzig.de.

Herz
|September 27, 2017
PubMed
Summary
This summary is machine-generated.

Cardiogenic shock complicating acute myocardial infarction involves a dangerous cycle of heart failure and inflammation. Current treatments focus on evidence-based guidelines, with ongoing debate on revascularization strategies.

Keywords:
Acute heart failureCardiogenic shockCirculatory supportMyocardial infarctionPrognosisRevascularization

More Related Videos

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

4.2K
The Intra-Aortic Balloon Pump
06:13

The Intra-Aortic Balloon Pump

Published on: February 5, 2021

25.1K

Related Experiment Videos

Last Updated: Feb 22, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.7K
Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

4.2K
The Intra-Aortic Balloon Pump
06:13

The Intra-Aortic Balloon Pump

Published on: February 5, 2021

25.1K

Area of Science:

  • Cardiology
  • Critical Care Medicine

Background:

  • Cardiogenic shock (CS) is a severe complication of acute myocardial infarction (AMI).
  • CS involves a complex pathophysiology including left heart failure, vasoconstriction, and systemic inflammation response syndrome (SIRS).
  • Understanding the shock spiral is crucial for effective intervention.

Purpose of the Study:

  • To review the pathophysiology, incidence, survival outcomes, and treatment options for CS post-AMI.
  • To synthesize evidence from randomized clinical trials and guideline recommendations for managing CS.
  • To address unresolved questions in interventional and surgical treatment strategies.

Main Methods:

  • Review of randomized clinical trials (RCTs) and current guideline recommendations.
  • Analysis of evidence for medical, interventional, and surgical treatment options.
  • Evaluation of circulatory support devices.

Main Results:

  • Acetylsalicylic acid (ASA) and heparin are often combined with prasugrel and ticagrelor.
  • Dobutamine is the first-line inotrope; norepinephrine is the preferred vasopressor.
  • Levosimendan did not demonstrate superiority over conventional treatments in RCTs.
  • Intra-aortic balloon pumps (IABP) are no longer recommended for acute heart failure (Class III).
  • Percutaneous mechanical circulatory support devices have not shown survival benefits compared to IABP due to bleeding complications.

Conclusions:

  • Interrupting the cardiogenic shock spiral is a primary treatment goal.
  • Treatment decisions should be guided by RCT evidence and current guidelines.
  • Complete revascularization versus culprit lesion-only revascularization remains an area of investigation.
  • Current evidence does not support routine use of IABP or percutaneous mechanical circulatory support for improved survival in CS post-AMI.