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Updated: Aug 11, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
Published on: April 9, 2014
[Retroviral infections by HIV-1, HIV-2 and AIDS-related complex in the Ivory Coast]
A Ouattara1, M A Rey, F Brun-Vésinet
1Laboratoire d'Epidémiologie et Immunovirologie des Tumeurs, Faculté de Médecine Alexis-Carrel, Lyon.
Abstract:
The study of 500 blood donors, of 23 prostitutes, 22 confirmed AIDS cases and 19 ARC patients in Abidjan showed that HIV-2 prevalence in blood donors (3.4%) was somewhat higher than that of HIV-1 (2.4%). Furthermore HIV-2 alone was found associated with 14% of AIDS cases and 21% of ARC, while HIV-1 was associated with 32% of the cases. Antibodies to HIV-1 and HIV-2 were found in 54% of AIDS and ARC cases, as well as in 48% of the prostitutes sera. These preliminary results suggest that HIV-2 is pathogenic, being causally involved in some AIDS cases and does not protect from HIV-1 pathogenic potential.
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