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Age-specific incidence and treatment patterns of head and neck cancer in the Netherlands-A cohort study
G B Halmos1, L Bras1,2, S Siesling3,4
1Department of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Objectives:
To explore the incidence and treatment pattern of head and neck cancer in different age groups.
Design:
Cohort study.
Setting:
Netherlands Cancer Registry.
Participants:
All new primary head and neck cancer cases diagnosed between 2010 and 2014 were included and categorised into different age groups.
Main Outcome Measures:
Tumour site, stage, treatment modality, location of diagnosis and treatment.
Results:
The study population was composed of 11 558 tumours. Oral cancer was the most common primary site (31%), followed by laryngeal (25%) and oropharyngeal cancer (22%). Ninety-six per cent of the entire study population was diagnosed and/or treated in a certified head and neck oncology centre which was lower in the 80+ population (92%). Multimodality treatment was less frequently applied with increasing age (eg oral cavity: 17% in 80+ vs 34% in 60-; P < .001). The percentage of patients not receiving tumour-directed treatment increased with age (eg oropharyngeal cancer: 25% in 80+ vs 6% in 80-; P < .001).
Conclusions:
This study confirms that less multimodal and tumour-directed treatment is applied with the increasing age of head and neck cancer patients.
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