Related Experiment Videos
Alpha-adrenoceptor blocking action of hymenin, a novel marine alkaloid
J Kobayashi1, H Nakamura, Y Ohizumi
1Mitsubishi-Kasei Institute of Life Sciences, Tokyo, Japan.
Experientia
|January 15, 1988
Abstract:
In the rabbit isolated aorta, hymenin (10(-6) M), a novel marine alkaloid, caused a parallel rightward shift of the dose-response curve for norepinephrine without affecting that for histamine or KCl, suggesting that hymenin is a competitive antagonist of alpha-adrenoceptors in vascular smooth muscles.