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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

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Genetics and mechanisms leading to human cortical malformations

Delfina M Romero1, Nadia Bahi-Buisson2, Fiona Francis1

  • 1INSERM UMR-S 839, 17 Rue du Fer à Moulin, Paris 75005, France; Sorbonne Universités, Université Pierre et Marie Curie, 4 Place Jussieu, Paris 75005, France; Institut du Fer à Moulin, 17 Rue du Fer à Moulin, Paris 75005, France.

Seminars in Cell & Developmental Biology
|September 28, 2017
PubMed

Keywords:
Atypical rare mutationsCortical malformationsExome sequencingHeterotopiaHuman in vitro culturesLissencephalyMicrocephalyNeuronal migrationPolymicrogyriaTubulinopathiesZIKV

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