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Interferon alpha-induced non-immune thyrotoxicosis treated by plasmapheresis

Zeynel Abidin Sayiner1, Ayten Eraydın2, Taylan Metin2

  • 1Department of Endocrinology and Metabolism, Gaziantep University, Gaziantep, Turkey.

BMJ Case Reports
|September 28, 2017
PubMed

Interferon-alpha (IFN-α) is an effective drug used for the treatment of chronic hepatitis C. So far its numerous side effects have been reported in the literature. It may be difficult to always put IFN-induced thyroid diseases into a single classic thyroid disease table. There are numerous atypical thyroid diseases due to IFN usage for hepatitis C virus. Herein, we present a case with a rare clinical table such as thyrotoxicosis observed following IFN-α therapy in a patient with euthyroid nodular thyroid without autoimmune thyroiditis findings and the use of therapeutic apheresis method for the treatment of disease.

Keywords:
hepatitis cthyroid diseaseunwanted effects / adverse reactions

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