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Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
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Ocular anatomic changes for different accommodative demands using swept-source optical coherence tomography: a pilot

José J Esteve-Taboada1, Teresa Ferrer-Blasco2, Miguel A Aloy3

  • 1Department of Optics and Optometry and Visual Science, University of Valencia, C/ Dr Moliner, 50, Burjassot, 46100, Spain. josejuan.esteve@uv.es.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|September 28, 2017
PubMed
Summary
This summary is machine-generated.

This study demonstrates how to measure ocular changes during accommodation using swept-source optical coherence tomography (SS-OCT). Significant changes in anterior chamber depth and lens thickness were observed with varying accommodative demands.

Keywords:
AccommodationAnterior chamberOptical coherence tomography

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Area of Science:

  • Ophthalmology
  • Biomedical Optics
  • Optical Coherence Tomography

Background:

  • Accurate measurement of ocular parameters is crucial for understanding visual function.
  • Accommodative changes can influence several intraocular dimensions.
  • Swept-source optical coherence tomography (SS-OCT) offers advanced capabilities for ocular biometry.

Purpose of the Study:

  • To assess changes in ocular parameters under different accommodative demands.
  • To evaluate the utility of a new SS-OCT based optical biometer for dynamic measurements.
  • To establish a practical methodology for measuring accommodative responses.

Main Methods:

  • A pilot study involving seven subjects was conducted.
  • Ocular parameters including anterior chamber depth (ACD) and lens thickness (LT) were measured using the IOLMaster 700 (SS-OCT).
  • A novel method using a tilted mirror was employed to induce accommodative demands of 0.0 D, 1.5 D, and 3.0 D.

Main Results:

  • No significant changes were observed in central corneal thickness (CCT), axial length (AL), white-to-white distance (WTW), or keratometric readings (K1, K2) across accommodative states.
  • Statistically significant changes in ACD and LT were detected with varying accommodative demands.
  • ACD and LT variations showed a strong linear correlation (R² ≥ 0.99) with changes in vergence.

Conclusions:

  • A practical methodology for assessing ocular parameter changes during accommodation using SS-OCT was successfully developed.
  • The findings of significant changes in ACD and LT align with previous research.
  • This technique provides a valuable tool for studying dynamic ocular responses.