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Induction of Hypoxia in Living Frog and Zebrafish Embryos
Published on: June 26, 2017
1Department of Oral Health Sciences, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
Abstract:
Posso-Terranova and Andrés (2017) used harlequin poison frogs to investigate the genetic basis of pigmentation evolution and variation. Using a candidate gene approach, they clearly delimited the origins and distribution of MC1R haplotypes and associated them with key pigmentation phenotypes on multiple levels. They demonstrated that MC1R-related cellular phenotypes and associated protein truncations evolved at least twice to produce dark dorsal skin colors in different clades.
Insights
Researchers studied poison frogs to understand how skin color evolves. They found that the melanocortin-1 receptor (MC1R) gene evolved multiple times, leading to dark skin in different frog groups.
Area of Science:
- Evolutionary biology
- Genetics
- Herpetology
Background:
- Pigmentation variation is crucial for species adaptation.
- The melanocortin-1 receptor (MC1R) gene is a key regulator of pigmentation in vertebrates.
- Understanding the genetic underpinnings of pigmentation evolution can reveal adaptive processes.
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