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Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

Biodegradable Materials and Metallic Implants-A Review.

Mythili Prakasam¹, Janis Locs², Kristine Salma-Ancane³

¹CNRS, Univ. Bordeaux, ICMCB, UPR 9048, F-33600 Pessac, France. mythili.prakasam@icmcb.cnrs.fr.

Journal of Functional Biomaterials

|September 29, 2017

Summary

Biodegradable biomaterials, including ceramics, polymers, and metal alloys, are advancing clinical applications. This review details their functions, properties, and challenges for future bioimplant development.

Keywords:

bioceramics biocomposites biodegradable metal alloys bioimplants

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Area of Science:

Biomaterials Science
Medical Engineering
Materials Science

Background:

Significant advancements in biomaterials over the past five decades have led to diverse clinical applications.
Current bioimplants utilize various forms including ceramics, glasses, polymers, composites, glass-ceramics, and metal alloys.
A key development is the design of materials that degrade or resorb within the body, eliminating the need for explantation.

Purpose of the Study:

To provide a comprehensive review of state-of-the-art biodegradable bioceramics, polymers, and metal alloys.
To discuss essential functions, critical properties, and influencing factors of these bioresorbable/biodegradable materials.
To highlight the challenges and future directions in the field of biodegradable biomaterials for implants.

Main Methods:

Literature review of recent progress in biomaterials and their clinical applications.
Focus on biodegradable and bioresorbable materials, including ceramics, polymers, and metal alloys.
Detailed discussion of material properties such as mechanical strength, biocompatibility, degradation rate, and corrosion resistance.

Main Results:

Biomaterials science has seen substantial progress, enabling a wide array of bioimplant options.
Biodegradable materials offer advantages by eliminating the need for secondary surgeries to remove implants.
Critical factors like mechanical properties, non-toxicity, surface modification, and scaffold design are crucial for effective bioimplants.

Conclusions:

Biodegradable biomaterials are crucial for advanced bioimplant development, offering functional integration and resorption.
Understanding material properties and overcoming current challenges are essential for optimizing clinical performance.
Continued research into biodegradable ceramics, polymers, and metal alloys will drive innovation in regenerative medicine and tissue engineering.