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[A woman with a persistent cough].
Nederlands Tijdschrift Voor Geneeskunde
|September 29, 2017
Summary
A rare Corynebacterium diphtheriae infection caused tracheal abnormalities and chronic cough in an unvaccinated woman. Antibiotic treatment successfully resolved the respiratory symptoms and lesions.
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Area of Science:
- Infectious Diseases
- Microbiology
- Pulmonology
Background:
- Corynebacterium diphtheriae is a bacterium typically associated with pharyngeal infections.
- Non-toxigenic strains are generally considered less virulent, causing localized symptoms.
Observation:
- A 54-year-old unvaccinated woman presented with chronic cough and a tracheal ulcer-like abnormality.
- Bronchoscopy confirmed the tracheal lesion, and cultures identified non-toxigenic Corynebacterium diphtheriae.
Findings:
- The case demonstrates a rare instance of non-toxigenic Corynebacterium diphtheriae causing significant respiratory tract pathology.
- Successful antibiotic therapy led to the resolution of both the infection and the observed tracheal abnormalities.
Implications:
- This case highlights the potential for non-toxigenic C. diphtheriae to cause unusual respiratory manifestations.
- It underscores the importance of considering diverse pathogens in unexplained respiratory symptoms, even in immunocompetent individuals.