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Usefulness of a novel higher brain dysfunction screening test for evaluating higher brain function in healthy persons
Akemi Hioka1,2, Yoshifumi Mizobuchi1,3, Yoshiteru Tada1
1Department of Neurosurgery, Institute of Biomedical Sciences, Tokushima University, Graduate School.
The Journal of Medical Investigation : JMI
|September 29, 2017
Summary
The higher brain dysfunction screening test (HIBRID-ST) effectively identifies age-related declines in cognitive function among healthy adults. This validated tool shows lower scores with increasing age, confirming its utility in assessing brain health.
Area of Science:
- Neuroscience
- Gerontology
- Cognitive Psychology
Background:
- Higher brain function is known to decline with age.
- The utility of the "higher brain dysfunction screening test" (HIBRID-ST) in healthy aging populations was previously unclear.
Purpose of the Study:
- To assess the effectiveness of HIBRID-ST in detecting age-related changes in higher brain function in healthy individuals.
- To validate HIBRID-ST as a tool for evaluating cognitive decline in aging.
Main Methods:
- Recruited 60 healthy participants, aged 20s to 70s, divided into six age groups.
- Administered HIBRID-ST, assessing orientation, memory, recall, awareness, and visual-spatial skills, including Trail Making and Kana-hiroi tests.
Main Results:
- A significant negative correlation (ρ = -0.68, p < 0.01) was found between participant age and total HIBRID-ST scores.
- Participants in their 70s scored significantly lower than those in their 20s-60s.
- Participants in their 60s scored significantly lower than those in their 20s-50s.
Conclusions:
- HIBRID-ST accurately detects age-related declines in higher brain function in healthy adults.
- The findings support HIBRID-ST's use in assessing cognitive changes associated with aging.
- Further research is recommended to evaluate HIBRID-ST in individuals with diagnosed higher brain dysfunction.

