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Kefir: a powerful probiotics with anticancer properties.

Mohammadreza Sharifi1, Abbas Moridnia2, Deniz Mortazavi3

  • 1Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, 81744-176, Iran. mo_sharifi@med.mui.ac.ir.

Medical Oncology (Northwood, London, England)
|September 29, 2017
PubMed
Summary

Kefir, a fermented milk product, shows significant potential in cancer prevention and treatment. Its bioactive compounds may inhibit tumor cell proliferation and induce apoptosis, offering therapeutic benefits.

Keywords:
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Area of Science:

  • Microbiology
  • Oncology
  • Nutritional Science

Background:

  • Probiotics and fermented foods, like kefir, are gaining scientific interest for health applications.
  • Kefir, originating from Caucasian and Tibetan regions, is produced by fermenting milk with kefir grains (yeast and bacteria).
  • Kefir grains possess various health benefits, including antibacterial, antifungal, anti-allergic, and anti-inflammatory properties.

Purpose of the Study:

  • To review the existing scientific literature on the anticancer properties of kefir.
  • To highlight kefir's potential role in cancer prevention and treatment strategies.

Main Methods:

  • Literature review of studies investigating kefir's effects on cancer.
  • Analysis of research on kefir's bioactive compounds, such as polysaccharides and peptides.
  • Examination of studies detailing kefir's impact on various cancer types.

Main Results:

  • Kefir exhibits potential anticancer effects through inhibition of tumor cell proliferation.
  • Bioactive compounds in kefir may induce apoptosis (programmed cell death) in cancer cells.
  • Studies indicate kefir's efficacy against colorectal cancer, malignant T lymphocytes, breast cancer, and lung carcinoma.

Conclusions:

  • Kefir demonstrates promising anticancer properties, warranting further investigation for clinical applications.
  • Dietary intake of kefir may contribute to cancer prevention and serve as an adjunct therapy.
  • The bioactive components of kefir are key to its observed anti-cancer activities.