Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Proofreading01:31

Proofreading

9.3K
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase...
9.3K
Proofreading01:43

Proofreading

61.7K
Overview
61.7K
Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

9.5K
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
9.5K
Mismatch Repair01:36

Mismatch Repair

44.0K
Overview
44.0K
Mismatch Repair01:20

Mismatch Repair

6.7K
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
6.7K
Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

8.1K
Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
8.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

The Amapola Test: description of a novel screening tool for visual alterations in primary care.

Family practice·2026
Same journal

Deferred prescribing in practice: an observational study in community pharmacies in France during 2024-5 and feedback from pharmacists.

Family practice·2026
Same journal

Assessing the risk of drug-induced corrected QT interval prolongation in primary care.

Family practice·2026
Same journal

Universal-offer HIV testing amongst patients undergoing blood tests in primary care: results from a multi-centre study.

Family practice·2026
Same journal

Sustainable healthcare knowledge, experience and curricular perspectives: a cross-sectional survey within the European Young Family Doctors Movement network.

Family practice·2026
Same journal

General practice care models and satisfaction in Australian residential aged care homes: a national survey of GPs, practice nurses, and managers.

Family practice·2026

Related Experiment Video

Updated: Feb 22, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

1.4K

Erratum

    Family Practice
    |September 29, 2017
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
    09:41

    Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

    Published on: June 17, 2014

    12.5K
    Surgical Correction for Pediatric Epiblepharon and Trichiasis
    03:59

    Surgical Correction for Pediatric Epiblepharon and Trichiasis

    Published on: July 8, 2025

    639

    Related Experiment Videos

    Last Updated: Feb 22, 2026

    Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
    03:25

    Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

    Published on: June 16, 2022

    1.4K
    Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
    09:41

    Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

    Published on: June 17, 2014

    12.5K
    Surgical Correction for Pediatric Epiblepharon and Trichiasis
    03:59

    Surgical Correction for Pediatric Epiblepharon and Trichiasis

    Published on: July 8, 2025

    639