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KRAS Alleles: The Devil Is in the Detail

Kevin M Haigis1

  • 1Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.

Trends in Cancer
|September 30, 2017
PubMed
Summary

KRAS mutations drive cancer, but targeting them is hard. This review explores differences between KRAS mutations, suggesting allele-specific therapies could be effective for cancer treatment.

Keywords:
KRASRASallelescancer geneticsoncogene

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