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Generalised joint hypermobility and neurodevelopmental traits in a non-clinical adult population
Martin Glans1, Susanne Bejerot2, Mats B Humble3
1, MD, Stockholm County Council, Stockholm, Sweden; School of Medical Sciences, Örebro University, Örebro, Sweden.
Background:
Generalised joint hypermobility (GJH) is reportedly overrepresented among clinical cases of attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD) and developmental coordination disorder (DCD). It is unknown if these associations are dimensional and, therefore, also relevant among non-clinical populations.
Aims:
To investigate if GJH correlates with sub-syndromal neurodevelopmental symptoms in a normal population.
Method:
Hakim-Grahame's 5-part questionnaire (5PQ) on GJH, neuropsychiatric screening scales measuring ADHD and ASD traits, and a DCD-related question concerning clumsiness were distributed to a non-clinical, adult, Swedish population (n=1039).
Results:
In total, 887 individuals met our entry criteria. We found no associations between GJH and sub-syndromal symptoms of ADHD, ASD or DCD.
Conclusions:
Although GJH is overrepresented in clinical cases with neurodevelopmental disorders, such an association seems absent in a normal population. Thus, if GJH serves as a biomarker cutting across diagnostic boundaries, this association is presumably limited to clinical populations.
Declaration Of Interest:
None.
Copyright And Usage:
© The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.
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