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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Endovascular Thrombectomy in Medium and Distal Vessel Occlusions: A Focused Guideline From the Society of Vascular and Interventional Neurology Guidelines and Practice Standards Committee.

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Related Experiment Video

Updated: Feb 22, 2026

Intracerebral Transplantation and In Vivo Bioluminescence Tracking of Human Neural Progenitor Cells in the Mouse Brain
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Update on cell therapy for stroke.

Cynthia L Kenmuir1, Lawrence R Wechsler1

  • 1Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Stroke and Vascular Neurology
|September 30, 2017
PubMed
Summary

Cell therapy shows promise for treating ischaemic stroke, potentially reversing neurological damage and reducing disability. Further research is needed to optimize this novel treatment for stroke patients.

Area of Science:

  • Neuroscience
  • Regenerative Medicine
  • Clinical Neurology

Background:

  • Ischaemic stroke is a major cause of death and disability worldwide.
  • Current acute treatments like thrombolytics and thrombectomy do not reverse established neurological damage.
  • There is a critical unmet need for therapies that can repair brain injury after stroke.

Purpose of the Study:

  • To review recent clinical trials on cell therapy for ischaemic stroke.
  • To evaluate the safety and efficacy of cell therapy in improving functional outcomes.
  • To identify areas for future research to optimize cell therapy for stroke treatment.

Main Methods:

  • Review of preclinical studies and recent clinical trials involving cell therapy in ischaemic stroke.
  • Analysis of reported safety data and functional outcome improvements.
Keywords:
cell therapystem cellstroke

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  • Identification of key variables influencing cell therapy effectiveness.

    • Main Results:

    • Preclinical data suggest cell therapy is safe and effective for functional recovery.
    • Recent clinical trials indicate safety and some outcome improvements with cell therapy.
    • Cell therapy presents a potential new avenue for reducing stroke-related disability.

    Conclusions:

    • Cell therapy offers a promising therapeutic strategy for post-stroke recovery.
    • Further investigation is required to optimize cell type, dosage, delivery, and timing.
    • Personalized approaches considering infarct characteristics are crucial for maximizing therapeutic benefits.