Diosmetin protects against retinal injury via reduction of DNA damage and oxidative stress

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Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
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Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

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Zeren Shen1,2, Jinjin Shao1, Jiabin Dai1

  • 1Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P.R. China.

Toxicology Reports
|September 30, 2017
PubMed

Keywords:
ADR, adriamycinAMD, age-related macular degenerationATP, adenosine triphosphateApoptosisCNV, choroidal neovascularisationChrysanthemumDIO, diosmetinDNA damageDiosmetinDiosmetin (PubChem CID5281612)Doxorubicin (PubChem CID31703)H&E, hematoxylin and eosinIC50, inhibition for 50% of the cellsIVI, intravitreal injectionOxidative stressPVR, proliferative vitreoretinopathyROS, reactive oxygen speciesRPE, retinal pigment epitheliumRetinal injuryRetinal pigment epithelium

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