[Treatment of cardiovascular disease with Xiongshao capsule]
Rong Yuan1,2, Yan Wang1,2, Wei-Hong Cong2
1Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China.
Insights
Xiongshao capsule, a traditional Chinese medicine, shows significant therapeutic effects in treating cardiovascular diseases like angina and atherosclerosis. This review highlights its potential in integrated medicine approaches for heart health.
Area of Science:
- Cardiology
- Pharmacology
- Traditional Chinese Medicine
Background:
- Cardiovascular diseases (CVDs) are a leading cause of mortality globally.
- Integrated traditional Chinese and Western medicine offers promising therapeutic strategies for CVDs.
- Xiongshao capsule, derived from Xuefu Zhuyu decoction, targets various cardiovascular conditions.
Purpose of the Study:
- To review basic and clinical studies on the efficacy of Xiongshao capsule in treating cardiovascular diseases.
- To provide a reference for the clinical application of Xiongshao capsule.
- To exemplify the development of new traditional Chinese medicines within an integrated medical framework.
Main Methods:
- Review of existing literature on Xiongshao capsule.
- Analysis of preclinical (basic) studies.
- Evaluation of clinical trial data and case studies.
Main Results:
- Xiongshao capsule demonstrates significant therapeutic effects in managing angina pectoris.
- The capsule is effective in preventing restenosis after percutaneous coronary intervention (PCI).
- Evidence suggests benefits in treating atherosclerosis and dyslipidemia.
Conclusions:
- Xiongshao capsule is a valuable therapeutic agent for cardiovascular diseases.
- Its application aligns with the principles of integrated traditional Chinese and Western medicine.
- Further research and clinical application are warranted to optimize its use.
Abstract:
Cardiovascular diseases have the characteristics of high morbidity and high mortality, and are recognized as the first cause of death by World Health Organization in World Health Statistics 2016. In recent years, traditional Chinese medicines have been widely applied in the treatment of cardiovascular diseases, while studies for integrated traditional Chinese and western medicines for treating cardiovascular diseases have made a great progress. Xiongshao capsule was developed by Academician Chen Keji according to classic formula Xuefu Zhuyu decoction and composed of effective parts of Rhizoma Ligusticum Wallichii and Radix Paeonia Rubra, with remarkable therapeutic effects on angina pectoris, restenosis after percutaneous coronary intervention(PCI), atherosclerosis, dyslipidemia and so on. In this review, basic and clinical studies for the effect of Xiongshao capsule in treating cardiovascular diseases were reviewed to provide reference for reasonable clinical use and example for new traditional Chinese medicine development and application under the guidance of theory of integrated traditional Chinese and western medicines.
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