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Updated: Feb 22, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Prenatal 3D sonography of an isolated lateral facial cleft
Mina Lee1, Young-Bok Ko1, Jung-Bo Yang1
1Department of Obstetrics and Gynecology, Chugnam National University Hospital, Chungnam National University School of Medicine, Daejeon, South Korea.
Abstract:
Lateral facial cleft is a rare congenital anomaly, but all affected infants require surgery under general anesthesia. Conventional 2-dimensional coronal view of the face, which is typically used for identification of facial clefts, has limitations with regard to detection of this anomaly. We describe a case of prenatal diagnosis of isolated lateral facial cleft made with 3D sonography and highlight the importance of this tool in the diagnosis of this rare facial deformity.
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