Jove
Visualize
Contact Us

Related Concept Videos

Cytoskeletal Linker Proteins - Plakins01:09

Cytoskeletal Linker Proteins - Plakins

2.9K
Plakins are large proteins with binding domains for microtubules, microfilaments, intermediate filaments, and membrane-associated protein complexes at cell junctions. Plakin functions are evolutionarily conserved and are primarily involved in organizing the different components of the cytoskeleton by crosslinking them to each other and connecting them to the cell-matrix and cell adhesion complexes. They are also known to interact with signal transducers, serve as scaffolds for signaling...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel Knotted Solenoid fold with order-shifted coil arrangement leads to nontrivial 3<sub>1</sub> topology.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Enhancing Image Quality in Dental-Maxillofacial CBCT: The Impact of Iterative Reconstruction and AI on Noise Reduction-A Systematic Review.

Journal of clinical medicine·2025
Same author

Universe of Lasso Proteins: Exploring the Limit of Entanglement of Proteins Predicted by AlphaFold.

Journal of molecular biology·2025
Same author

AlphaLasso-a web server to identify loop and lasso motifs in 3D structure of biopolymers.

Nucleic acids research·2025
Same author

Theta-curves in proteins.

Protein science : a publication of the Protein Society·2024
Same author

Everything AlphaFold tells us about protein knots.

Journal of molecular biology·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Feb 22, 2026

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline
11:09

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline

Published on: January 5, 2017

18.1K

PyLasso: a PyMOL plugin to identify lassos.

Aleksandra M Gierut1,2, Wanda Niemyska1, Pawel Dabrowski-Tumanski1,3

  • 1Centre of New Technologies, University of Warsaw, Banacha 2c, Warsaw, 02-097, Poland.

Bioinformatics (Oxford, England)
|September 30, 2017
PubMed
Summary
This summary is machine-generated.

Researchers have discovered that about 4% of proteins form lasso structures. A new tool, PyLasso, helps identify and analyze these molecular entanglements in proteins and other polymers.

More Related Videos

Author Spotlight: Exploring Cellular Processes by Modeling Ligands in Cryo-EM Maps
09:30

Author Spotlight: Exploring Cellular Processes by Modeling Ligands in Cryo-EM Maps

Published on: July 19, 2024

2.2K
Au-Interaction of Slp1 Polymers and Monolayer from Lysinibacillus sphaericus JG-B53 - QCM-D, ICP-MS and AFM as Tools for Biomolecule-metal Studies
08:29

Au-Interaction of Slp1 Polymers and Monolayer from Lysinibacillus sphaericus JG-B53 - QCM-D, ICP-MS and AFM as Tools for Biomolecule-metal Studies

Published on: January 19, 2016

11.8K

Related Experiment Videos

Last Updated: Feb 22, 2026

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline
11:09

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline

Published on: January 5, 2017

18.1K
Author Spotlight: Exploring Cellular Processes by Modeling Ligands in Cryo-EM Maps
09:30

Author Spotlight: Exploring Cellular Processes by Modeling Ligands in Cryo-EM Maps

Published on: July 19, 2024

2.2K
Au-Interaction of Slp1 Polymers and Monolayer from Lysinibacillus sphaericus JG-B53 - QCM-D, ICP-MS and AFM as Tools for Biomolecule-metal Studies
08:29

Au-Interaction of Slp1 Polymers and Monolayer from Lysinibacillus sphaericus JG-B53 - QCM-D, ICP-MS and AFM as Tools for Biomolecule-metal Studies

Published on: January 19, 2016

11.8K

Area of Science:

  • Biophysics
  • Computational Biology
  • Polymer Science

Background:

  • Macromolecular entanglement is a key phenomenon in various scientific disciplines.
  • Recent discoveries reveal that approximately 4% of proteins exhibit novel entangled motifs known as lassos.

Purpose of the Study:

  • To introduce PyLasso, a PyMOL plugin designed for identifying and analyzing lasso structures.
  • To provide a tool for researchers studying entanglement in diverse systems.

Main Methods:

  • Development of the PyLasso plugin for PyMOL.
  • Utilizing PyMOL's capabilities for visualization and analysis of macromolecular structures.

Main Results:

  • PyLasso enables the identification of lasso motifs in proteins and other (bio)polymers.
  • The plugin facilitates the analysis of properties associated with these entangled structures.

Conclusions:

  • PyLasso is a valuable tool for researchers in macromolecular modeling, structure prediction, and polymer properties.
  • The tool supports studies on entanglement in biological, physical, and mathematical systems.