Osteotomy Site Grafting in Bilateral Sagittal Split Surgery With Bioactive Glass S53P4 for Skeletal Stability

Area of Science:

• Oral and Maxillofacial Surgery
• Biomaterials Science
• Regenerative Medicine

Background:

• Orthognathic surgery aims for optimal occlusion and facial aesthetics.
• Large mandibular advancements risk insufficient healing and tissue support at osteotomy sites.
• Augmentation strategies are crucial for enhancing stability, bone regeneration, and aesthetics.

Purpose of the Study:

• To evaluate bioactive glass S53P4 granules as a filling material for osteotomy site defects in large mandibular advancements.
• To assess the safety, efficacy, and long-term outcomes of S53P4 in bilateral sagittal split osteotomies.

Main Methods:

• Prospective clinical study involving 25 patients with Class II dentoskeletal deformities.
• Bilateral sagittal split osteotomies were performed and augmented with S53P4 granules (8-15 mm defects).
• Clinical follow-up averaged 33 months; radiological follow-up (CBCT) averaged 24 months.

Main Results:

• Excellent clinical and radiological outcomes regarding bone healing, regeneration, and osteotomy site stability.
• 96% of osteotomy sites showed good soft tissue support and excellent aesthetic results.
• Stable occlusion was achieved in 88% of patients.

Conclusions:

• Bioactive glass S53P4 is a safe and effective grafting material for significant mandibular advancements.
• S53P4 promotes reliable bone regeneration and provides long-term stability at the osteotomy site and inferior mandibular border.
• The material enhances aesthetic outcomes by improving soft tissue support in orthognathic surgery.