[Effect of prolonged inhalation of acetic acid vapors on several human functional parameters]

Test subjects were continuously exposed to acetic acid vapors which form a constant component of enclosed atmospheres. The inhalation time was 15 to 22 days at concentrations of 5, 10 and 15 mg/m3 or 10 days at a concentration of 26 mg/m3. Physiological parameters showed statistically significant changes at concentrations of 15 and 26 mg/m3. It is suggested that the changes are not adaptive but have been produced by the adverse effect of acetic acid vapors on the human body. It is therefore concluded that the 15 mg/m3 concentration is threshold and the 5 and 10 mg/m3 concentrations are ineffective in terms of the tests used. The most sensitive method is measurement of hydrocarbons (C2-C5), especially ethylene, in the exhaled air.