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Related Experiment Video

Updated: Feb 22, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Man with leg rash.

Michael Huynh Hwang¹, Ziyad Khesbak¹, Yiju Teresa Liu¹

¹Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, USA.

Emergency Medicine Journal : EMJ

|October 1, 2017

Summary

This summary is machine-generated.

A man presented with a painful, blistering thigh rash and systemic symptoms. This case highlights the importance of considering specific diagnoses for rapidly progressing skin lesions.

Keywords:

musculo-skeletal soft tissue infection ultrasound

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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

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Published on: December 15, 2011

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Area of Science:

Dermatology
Emergency Medicine
Infectious Disease

Background:

A 51-year-old male presented with acute onset of a painful, erythematous, and vesicular rash on his bilateral thighs.
Associated symptoms included paresthesias, pruritus, fever, vomiting, and diarrhea.

Observation:

Physical examination revealed an 8x8 cm violaceous patch with vesicles, erythema, and induration on the left thigh, and a smaller, similarly tender lesion on the right thigh.
Bedside ultrasound imaging of the affected areas was performed.

Findings:

The clinical presentation and diagnostic imaging were crucial in differentiating between potential causes of the patient's rash.
Differential diagnoses included herpes zoster, cellulitis, necrotizing fasciitis, and bullous pemphigoid.

Implications:

Prompt and accurate diagnosis of rapidly evolving skin conditions is critical for effective management and patient outcomes.
This case underscores the need for a comprehensive approach, integrating clinical findings and diagnostic tools in emergency medicine settings.