[Animal models of premature ejaculation: Advances in studies]

Premature ejaculation (PE) is a commonest male sexual dysfunction clinically, with a complex pathogenesis and unsatisfactory treatment results. To clarify the etiology of PE is essential for the improvement of the therapeutic effect, and the animal model is an important tool for investigating its pathogenesis and treatment protocols. Currently there are various animal models for this purpose, each with its own characteristics and some suitable for animal experiments only. The application value of an animal model of PE depends on its repeatability, efficiency, and ability of fully simulating the clinical features of humans. This paper presents an overview on the most commonly used animal models of PE, compares their advantages and disadvantages, and provides some evidence for choosing the most suitable ones for PE studies.