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Pulmonary Function and Exercise Capacity in Patients With Flat Chests After Lung Transplantation
Ryo Miyoshi1, Toyofumi F Chen-Yoshikawa1, Akihiro Takahagi1
1Department of Thoracic Surgery, Kyoto University, Kyoto, Japan.
The Annals of Thoracic Surgery
|October 2, 2017
Summary
Lung transplantation in patients with flat chests shows poorer pulmonary function but equivalent exercise capacity. Chest shape significantly improves post-transplant, indicating acceptable outcomes are possible.
Area of Science:
- Thoracic surgery
- Pulmonary medicine
- Transplantation immunology
Background:
- Severe chest wall deformities are typically contraindications for lung transplantation.
- The impact of flat chests on post-lung transplant exercise capacity and pulmonary function remains unclear.
Purpose of the Study:
- To investigate the relationship between preoperative thoracic shape and postoperative functional outcomes in lung transplant recipients.
- To assess exercise capacity and pulmonary function in patients with flat chests compared to those with normal chests after lung transplantation.
Main Methods:
- Bilateral living-donor lobar lung transplantation recipients (n=20) were evaluated.
- Patients were categorized into flat chest (anteroposterior to transverse diameter ratio ≤1:3) and normal chest groups.
- Postoperative graft function was analyzed in relation to preoperative thoracic morphology.
Main Results:
- The flat chest group exhibited significantly lower postoperative forced vital capacity (FVC) compared to the normal chest group at 1 year (p=0.002).
- No significant differences in 6-minute walk distances were observed between the groups.
- The flat chest group showed a significant increase in the anteroposterior to transverse diameter ratio post-transplantation (p=0.02).
Conclusions:
- Patients with flat chests have reduced postoperative pulmonary function but comparable exercise capacity after lung transplantation.
- Flat chest severity demonstrated significant improvement following lung transplantation.
- Lung transplantation is feasible in patients with flat chests, yielding acceptable functional outcomes.
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