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Current Radiographic Iodinated Contrast Agents

Maria Vittoria Spampinato1, Ahad Abid2, Maria Gisele Matheus1

  • 1Department of Radiology and Radiological Science, Medical University of South Carolina, 96 Jonathan Lucas Street MSC 323, Charleston, SC 29425, USA.

Magnetic Resonance Imaging Clinics of North America
|October 2, 2017
PubMed

Millions of radiologic examinations requiring the use of iodinated contrast are performed yearly in North America. Triiodobenzoic acid, the contrast agent molecule currently in use, is a benzene ring covalently bonded to the 3 iodine atoms. Iodinated contrast media can be divided in 4 categories: ionic monomers, ionic dimers, nonionic monomer, and nonionic dimers. Currently, second- and third-generation nonionic low-osmolar and iso-osmolar contrast media are used in clinical practice. The search for a safer and more effective iodinated contrast agents remains an ongoing challenge and important research topic.

Keywords:
Computed tomographyContrast mediaDigital subtraction angiographyIodinated contrast agentsIodineTriiodobenzoic acid

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