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Contrast Agents for MR Imaging.

Ferenc Czeyda-Pommersheim1, Diego R Martin1, James R Costello1

  • 1Department of Medical Imaging, University of Arizona, 1501 N Campbell Avenue, PO Box 245067, Tucson, AZ 85724-5067, USA.

Magnetic Resonance Imaging Clinics of North America
|October 2, 2017
PubMed
Summary
This summary is machine-generated.

Magnetic resonance (MR) imaging contrast agents, including gadolinium-based, manganese, and iron agents, are vital for diagnosis. These agents are generally safe and well-tolerated, with a low incidence of adverse events, making them suitable for various clinical questions.

Keywords:
Contrast-enhanced MR imagingContrast-related adverse eventsGadolinium-based MR imaging contrastIron-based MR imaging contrastManganese-based MR imaging contrastRadiographic contrast

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Area of Science:

  • Radiology and Medical Imaging
  • Pharmacology

Background:

  • Contrast media are indispensable tools in modern Magnetic Resonance (MR) imaging.
  • A diverse range of contrast agents is now available for clinical application.
  • MR contrast agents offer a favorable safety profile compared to Computed Tomography (CT) contrast media.

Purpose of the Study:

  • To review the pharmacology of commonly used intravenous and oral MR contrast agents.
  • To outline the clinical indications for these MR contrast agents.
  • To discuss the common adverse events associated with MR contrast agents.

Main Methods:

  • Review of current literature on MR contrast agents.
  • Analysis of pharmacology, indications, and adverse events.
  • Focus on gadolinium-based, manganese-based, iron-based, and oral contrast agents.

Main Results:

  • MR contrast agents can be tailored for specific clinical applications.
  • Gadolinium-based, manganese-based, and iron-based agents are frequently used intravenously.
  • Common oral contrast agents are also utilized in MR imaging.

Conclusions:

  • MR contrast agents are well-tolerated with a low incidence of adverse events.
  • Understanding the pharmacology, indications, and potential adverse events is crucial for safe clinical practice.
  • This review provides essential information on contemporary MR contrast agents.