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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

552
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Related Experiment Video

Updated: Feb 22, 2026

Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation
10:56

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Published on: July 23, 2014

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Pediatric cardiac transplantation.

Thomas D Ryan1, Clifford Chin1

  • 1Division of Cardiology, The Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave-MLC 2003, Cincinnati, Ohio 45229.

Seminars in Pediatric Surgery
|October 2, 2017
PubMed
Summary
This summary is machine-generated.

Pediatric heart transplantation is a last resort for children with end-stage heart failure, offering improved survival rates. This life-saving procedure is for those with limited options and predicted short life expectancy.

Keywords:
HeartPediatricTransplantation

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Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Transplantation Medicine

Background:

  • Heart transplantation is a critical intervention for pediatric patients with end-stage heart failure.
  • Indications include diverse etiologies and potential end-organ dysfunction unresponsive to other therapies.
  • Understanding heart failure in children, especially with congenital heart disease, is complex, involving systolic/diastolic dysfunction or single ventricle physiology.

Purpose of the Study:

  • To define the role and outcomes of heart transplantation in pediatric patients.
  • To outline criteria for selecting appropriate candidates for pediatric heart transplantation.
  • To review contemporary survival rates and long-term prognosis post-transplant.

Main Methods:

  • Retrospective analysis of pediatric heart transplant recipients.
  • Review of patient selection criteria and management protocols.
  • Evaluation of survival data and long-term outcomes.

Main Results:

  • Pediatric heart transplantation demonstrates significant survival improvements over time.
  • Contemporary 1- and 5-year survival rates are approximately 90% and 80%, respectively.
  • Careful patient selection is crucial for successful outcomes.

Conclusions:

  • Heart transplantation is a viable, life-extending option for select pediatric patients with end-stage heart failure.
  • Improved survival rates underscore the efficacy of modern pediatric heart transplant protocols.
  • Continued research and optimized selection criteria will further enhance outcomes for these complex patients.