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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

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Pediatric liver transplantation

Alex G Cuenca1, Heung Bae Kim2, Khashayar Vakili3

  • 1Department of Surgery, Boston Children's Hospital, 300 Longwood Ave, Fegan 3, Boston 02115, MA.

Seminars in Pediatric Surgery
|October 2, 2017
PubMed

Insights

Pediatric liver transplantation outcomes have significantly improved, with over 85% 5-year survival. Advances in surgical techniques and multidisciplinary care enhance graft survival and broaden transplant indications.

Area of Science:

  • Pediatric Hepatology
  • Transplant Surgery
  • Immunology

Background:

  • Pediatric liver transplantation has seen major advancements in recent decades.
  • Surgical refinements, including living donor and split-liver grafts, have increased organ availability.
  • Multidisciplinary team care is crucial for pediatric transplant recipients.

Purpose of the Study:

  • To review current indications for pediatric liver transplantation.
  • To discuss surgical considerations and post-operative complications.
  • To outline long-term outcomes and challenges in pediatric liver transplant patients.

Main Methods:

  • Review of recent literature on pediatric liver transplantation.
  • Analysis of surgical techniques and graft utilization.
  • Examination of survival rates and morbidity associated with immunosuppression and rejection.

Main Results:

  • Pediatric liver transplant patients now achieve over 85% 5-year survival.
  • Expanded indications for transplantation have been established.
  • Long-term morbidity is primarily linked to immunosuppression and chronic rejection.

Conclusions:

  • Pediatric liver transplantation has evolved significantly, offering improved survival rates.
  • Continued advancements in surgical approaches and care models are vital.
  • Managing long-term complications remains a key focus for improving patient quality of life.

Keywords:
LiverPediatricSplit liverTransplant

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