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Quantitative Ultrasonography Measurements of the Phalanges in Adolescents: A Mixed Longitudinal Study
Anderson M de Moraes1, Humberto M Carvalho2, Ezequiel M Gonçalves3
1Department of Physical Education, Pontifical Catholic University of Campinas, Campinas, Brazil; Laboratory of Growth and Development, Center for Investigation in Pediatrics (CIPED), Faculty of Medical Sciences (FMS), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Abstract:
This study examined the effect of pubertal development on Amplitude Dependent Speed of Sound (AD-SoS), accounting for the growth in stature among adolescents. A mixed-longitudinal design with 3 assessments across a 15-mo period in 439 adolescents (girls: 215; boys: 224) aged 9-16 y was used. Bayesian multilevel models were used to describe gender-specific AD-SoS variations among participants during pubertal years. Substantial increments in AD-SoS during pubertal years were observed in both genders. AD-SoS changes were positively related to stature, and the rate of stature growth per year. Quantitative ultrasonography was sensible to describe age-related changes of bone mass during pubertal development. It seemed clinically reliable to use AD-SoS in the study of bone growth and development.

