Identification of Galectin-2-Mucin Interaction and Possible Formation of a High Molecular Weight Lattice

Mayumi Tamura1, Dai Sato1, Moeko Nakajima1

  • 1Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.

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Laminins are the Adhesive Proteins of Basal Lamina

Laminins are heterotrimeric proteins with high molecular mass found in the extracellular matrix. Each laminin molecule is composed of three chains, viz. alpha, beta, and gamma, coded by five, four, and three paralogous genes, respectively. Laminins are categories based on the compositions of the three chains.
In humans, the five forms of alpha chains are LAMA 1, LAMA 2, LAMA 3, LAMA 4, and LAMA 5. The four forms of beta chains are LAMB 1, LAMB 2, LAMB 3, and LAMB 4. The three forms of gamma...
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