Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

406
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
406
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

427
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
427
Positron Emission Tomography01:29

Positron Emission Tomography

7.8K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
7.8K
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

1.8K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.8K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

640
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
640
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

564
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
564

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incremental Prognostic Value of Cardiac Magnetic Resonance Beyond Biomarker Staging in Transthyretin Cardiac Amyloidosis.

European heart journal. Cardiovascular Imaging·2026
Same author

Correction to: 2025 ACC/AHA/ASE/ASNC/SCCT/SCMR Advanced Training Statement on Advanced Cardiovascular Imaging: A Report of the ACC Competency Management Committee.

Circulation. Cardiovascular imaging·2026
Same author

Semaglutide Reverses Ectopic Lipid Accumulation, Impaired Myocardial Perfusion Reserve, and Diastolic Dysfunction in a Mouse Model of Cardiometabolic Heart Disease.

JACC. Basic to translational science·2026
Same author

Cardiac Magnetic Resonance to Define Myocardial Structure in Obesity-Associated Heart Failure.

Current cardiology reports·2026
Same author

Cardiac magnetic resonance imaging diastolic function assessment in preserved ejection fraction and absence of late gadolinium enhancement.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance·2026
Same author

AI-Driven Quantitative Coronary CT Angiography in Suspected Coronary Artery Disease: Multicenter CONFIRM2 Registry.

JACC. Advances·2026

Related Experiment Video

Updated: Feb 22, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

20.2K

Update on Computed Tomography Myocardial Perfusion Imaging.

Amita Singh1, Victor Mor-Avi1, Amit R Patel1,2

  • 1Department of Medicine, University of Chicago Medicine, 5758 South Maryland Avenue, MC9067, Chicago, IL 60637, USA.

Current Cardiovascular Imaging Reports
|October 3, 2017
PubMed
Summary
This summary is machine-generated.

Computed tomography coronary angiography (CTCA) assesses coronary artery anatomy. Stress CT myocardial perfusion imaging (CT-MPI) now evaluates stenosis severity, improving coronary artery disease diagnosis.

Keywords:
Cardiac computed tomographyMyocardial perfusionPharmacologic stress testing

More Related Videos

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

4.4K
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

11.2K

Related Experiment Videos

Last Updated: Feb 22, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

20.2K
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

4.4K
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

11.2K

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Diagnostic Cardiology

Background:

  • Coronary CT angiography (CCTA) is a validated non-invasive method for diagnosing coronary artery disease (CAD).
  • A key limitation of CCTA is its reduced ability to identify physiologically significant stenoses, often necessitating further functional testing.
  • Stress CT myocardial perfusion imaging (CT-MPI) is an emerging technique designed to detect flow-limiting stenoses.

Purpose of the Study:

  • To review the role of CT-MPI as an adjunctive tool to CCTA.
  • To highlight the combined capability of CCTA and CT-MPI in assessing both coronary anatomy and the physiological significance of stenoses.
  • To discuss the diagnostic accuracy and potential future applications of CT-MPI in CAD management.

Main Methods:

  • Review of current literature on CT-MPI and its comparison with established diagnostic modalities.
  • Analysis of studies demonstrating the feasibility and accuracy of CT-MPI for detecting flow-limiting stenoses.
  • Evaluation of the combined diagnostic power of CCTA and CT-MPI.

Main Results:

  • The combination of CCTA and CT-MPI enables simultaneous assessment of coronary anatomy and stenosis significance.
  • CT-MPI has shown feasibility and diagnostic accuracy comparable to reference standards like SPECT, CMR, and invasive angiography.
  • Studies indicate CT-MPI can identify physiologically significant stenoses, addressing a limitation of CCTA alone.

Conclusions:

  • CT-MPI is transforming cardiac CT from an anatomical assessment tool to one capable of evaluating functional significance.
  • While standardization of acquisition and interpretation is ongoing, CT-MPI shows promise as a powerful adjunct to CCTA.
  • Further validation is expected to establish CT-MPI as a key component in managing patients with suspected coronary artery disease.