Related Experiment Video
Updated: Feb 22, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Clinicals And Upper Airway Characteristics in Obese Children with Obstructive Sleep Apnea
Eli O Martinelli1, Fernanda Louise M Haddad1, Renato Stefanini1
1Universidade Federal de São Paulo.
Insights
Obesity in children is linked to a high rate of obstructive sleep apnea (OSA). Enlarged tonsils and a high Mallampati score were identified as key factors associated with OSA in this pediatric group.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Otolaryngology
Background:
- Obesity is a known risk factor for obstructive sleep apnea (OSA) in adults.
- The association between obesity and OSA in children is less understood and remains controversial.
- This study investigates the clinical and upper airway characteristics of obese children with and without OSA.
Purpose of the Study:
- To compare clinical and upper airway characteristics between obese children with and without OSA.
- To identify factors associated with OSA in obese children.
Main Methods:
- A prospective cohort study included 44 obese children (BMI > 95th percentile).
- Data collected via questionnaires, physical examination, nasofibrolaryngoscopy, polysomnography, and allergy testing.
- Logistic regression analysis was used to identify associated factors.
Main Results:
- Obstructive sleep apnea (OSA) was diagnosed in 43% of the obese children studied.
- No significant differences were found in clinical or allergic parameters between groups.
- Hypertrophy of pharyngeal and palatine tonsils, and a modified Mallampati index of class III/IV were associated with OSA.
Conclusions:
- The prevalence of OSA is high in this cohort of obese children.
- Adenotonsillar hypertrophy and a modified Mallampati index of class III/IV are significant factors associated with OSA in obese children.
Introduction:
Obesity is a factor that is strongly related to the occurrence of obstructive sleep apnea (OSA) in adults, although this association remains controversial for children.
Objective:
The aim of this study was to compare the clinical and upper airway charactheristics, obtained by questionnaires, physical examination and laboratory tests, among obese children with and without OSA.
Method:
This was aprospective cohort study. 44 obese children (body mass index above the 95th percentile) were included in the study. Questionnaires, physical examination of the upper airway, nasofibrolaryngoscopy, polysomnography, and laboratory allergic tests were performed.
Results:
There were 22 male patients (50%), and the mean age was 7.6±2.5 years. OSA was present in 19 (43%) patients. There were no statistically significant differences between the groups with and without OSA, in relation to clinical or laboratory allergic parameters. For the upper airway assessments, hypertrophy of the pharyngeal (p=0.001) and palatine (p=0.049) tonsils were the only parameters associated with OSA, and a modified Mallampati index of class III/IV also demonstrated a tendency towards being statistically associated with OSA (p=0.081). Moreover, these findings were confirmed to be factors associated with OSA in this group of children according to a logistic regression analysis.
Conclusions:
The occurrence rate of OSA in this obese pediatric population was high. Adenotonsillar hypertrophy and a modified Mallampati index of class III/IV were the factors associated with OSA.
Related Concept Videos
Sleep Apnea
The condition is more prevalent among...
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...
Other Pulmonary Disorders
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Obesity

