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Staphylococcal infection in Malaysian hospitals
1Department of Microbiology, Faculty of Medicine, National University, Malaysia.
The Journal of Hospital Infection
|February 1, 1988
Summary
Staphylococcal infections are prevalent in Malaysian hospitals, often causing serious illness. Many Staphylococcus aureus strains show resistance to common antibiotics like penicillin and methicillin.
Area of Science:
- Microbiology
- Infectious Diseases
- Hospital Epidemiology
Background:
- Staphylococcal infections pose a significant threat in healthcare settings.
- Prevalence data for staphylococcal isolates and associated diseases in Malaysian hospitals are crucial for public health.
- Understanding antimicrobial resistance patterns is vital for effective treatment strategies.
Purpose of the Study:
- To determine the prevalence of staphylococcal isolates in Malaysian hospitals.
- To analyze the clinical significance of staphylococcal infections.
- To assess the antimicrobial resistance patterns of staphylococcal isolates, particularly Staphylococcus aureus.
Main Methods:
- A survey was conducted across 22 Malaysian hospitals.
- Blood cultures were analyzed for the presence of staphylococci.
- Isolates were further analyzed for clinical significance and antimicrobial susceptibility testing was performed.
Main Results:
- Staphylococci were isolated from nearly 40% of positive blood cultures in Malaysian hospitals.
- Approximately 70% of Staphylococcus aureus and 16% of coagulase-negative staphylococci were linked to significant disease.
- High rates of resistance to penicillin (40-100%) and methicillin (up to 25%) were observed in Staphylococcus aureus.
Conclusions:
- Staphylococcal infections are a common and serious issue in Malaysian hospitals.
- The high prevalence of antibiotic resistance, including methicillin resistance, necessitates urgent attention.
- Effective infection control and treatment strategies are required to combat staphylococcal infections and resistance.